Study on preparation and slow release properties of Magnesium-Al hydrotalcite with alanine intercalation

The precursors of Mg-Al hydrotalcite (Mg/Al-LDHs-NO3) were prepared by low saturation coprecipitation method (constant pH method). In addition, alsine-intercalated magnesium-aluminum (LDHs-Ala) was synthesized pH) and nucleation/crystallization isolation methods when the value higher than isoelectric point alanine. release properties alanine intercalated hydrotalc in simulated gastric fluid (hydrochloric acid solution with pH=1.5) intestinal (phosphate pH=7.4) measured spectrophotometer vitro. results showed that LDHs-Ala had good slow-release Then sodium alginate used to coated for slow fluid. It can be concluded has a rate fluid, but performance is expected targeted agent, which applied biomedicine.